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KMID : 0390020080180040349
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Pediatric Allergy and Respiratory Disease
2008 Volume.18 No. 4 p.349 ~ p.357
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Prevalence Rate of Sensitization to Cat Allergen in Children with Nasal Symptoms in Kunpo city.
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Park Yang
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Abstract
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Purpose:To investigate the prevalence rate of sensitization to indoor allergens, especially cat allergen in children with nasal symptoms in Kunpo city.
Methods:This study was a retrospective analysis of our radioallergosorbent test (RAST) database. We included 926 children with nasal symptoms between 3 months and 14 years of age. They underwent RAST which included 5 indoor and 4 food allergens. They were grouped according to age (0 to 3 years, 3 to 6 years, 6 to 9 years, 9 to 15 years). We calculated the prevalence rate of that sensitization according to age groups.
Results: Among the patients, 50.4% had the sensitization to at least > or =1 allergen of the RAST. The prevalence rate of sensitization increased according to the age group (P<0.05). The most common indoor allergen was Dermatophagoides farinae (D.f.) (22.6%), followed by cat (22.5%) and Dermatophagoides pteronyssinus (D.p.) (17.4%). Especially in the 0 to 3 age group, cat allergen (22.1%), was the predominant allergen, followed by dog (18.1%) and D.f. (8.7%). Among 926 patients, the rate of cat ownership was only 0.43%. The most common food allergen was pork (15.7%), followed by milk (4.9%) and egg white (3.2%). Pearsons test revealed significant correlation between cat and pork (r=0.563, P=0.000).
Conclusion: This study shows a high rate of sensitization to cat allergen especially the 0 to 3 age group. It might be caused by exposure to wild cat in the community. We need to design a policy to reduce airborne cat allergen in the community.
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KEYWORD
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Cat allergen, Children, Indoor allergen, Nasal symptom, Prevalence, Sensitization
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